Massachusetts arrest warrants do not expire. However, they can be cancelled in one of three ways, according to Rule 6(c)(4) of the Massachusetts Rules of Criminal Procedure.
First, the warrant will end after the police arrest the named suspect and return the executed warrant to the court that issued it.
Second, the court that issued the warrant may cancel it before the suspect has been detained.
Lastly, the district attorney’s office may file a motion with the issuing court requesting that the court cancel the warrant. It is left to the judge’s discretion whether the motion will be allowed and the warrant cancelled.
For more on arrests, both with and without a warrant, see my blog post: The Power to Arrest in Massachusetts.